What does the ENBIOSIS Microbiome Analysis Report Tell Us?

The number and type of bacteria that live within us in our intestines give important clues about our health and quality of life. In the very near future, it will be possible to detect many diseases early on by examining only the microorganisms in the stool. Our lifestyle and the environmental factors we are exposed to cause our microbiome to change and differentiate into a structure that is unique to us. It is known that these transformations in our microbiome are reflected in our health condition over time as positive or negative changes. In other words, in order to ensure our microbiome does not develop a profile that will adversely affect our health, revealing the current profile of our microbiome, taking steps to protect it, and managing it properly prove to be important steps for healthy life management and a proactive lifestyle that protects our body from diseases. The ENBIOSIS Microbiome Analysis Report is a new-generation technology that provides you with information on the current state of your microbiome and assesses it for certain health parameters.

The microbiome analysis report, which we have designed to recognize your microbiome and discover its effects on your current health, presents the following results to you:

  • your unique microbiome diversity,
  • the bacteria it hosts (taxonomic analysis),
  • health profile statistics of individuals with similar microbiomes, and
  • gut scores that provide important insights into your microbiome health.

Thanks to this analysis report, you will first learn whether your gut hosts a bacterial population rich enough for your health, what these bacteria are, and their main characteristics. Then, statistics about the health status of people whose microbiome is most similar to yours and which health problems they encounter most will be generated for you from a large pool from Turkey and across the world. Finally, you will get a report that highlights the scores that we find important for your health status and your condition compared to other samples in the pool. This report is presented to paint a general picture of your microbiome health and share it with you. By evaluating the results of this report, ENBIOSIS technology creates the personalized dietary guidelines needed to transform your existing microbiome profile into a healthier one.

Your Microbiome Diversity: There are trillions of bacteria living in our gut. Microbiome diversity is a measure of the diversity of the bacteria in our gut and the extent of the homogeneity of each species. Since individuals with high microbiome diversity have a richer metabolic activity in their gut, increasing microbiome diversity has a directly positive affect on health. The diversity score found in the microbiome analysis report evaluates the extent to which the microbiome has these characteristics compared to the population.

Taxonomic Analysis: Bacteria in the microbiome and their numbers are presented using the taxonomy of phylum (supergroup where closely related classes are grouped), family (supergroup where closely related genera are grouped), and genus (supergroup formed by grouping closely related species). You can evaluate your own profile in comparison with the profile of the general population and healthy individuals using these distribution charts. It is also possible to evaluate the sufficiency/deficiency of these bacteria by comparing the values of the bacteria known to be beneficial for your health with the mean scores of other samples.

Similar Profiles: It is expected that individuals with a similar gut profile to yours are also similar in terms of features related to health quality based on the microbiome. Therefore, the microbiome analysis report presents health/lifestyle statistics of individuals with the most similar microbiome in the pool. These statistics provide you with the opportunity to assess potential health risks.

Gut Scores: Recent scientific studies have discovered that certain health parameters are closely related to the microbiome. Therefore, it is possible to make accurate predictions by evaluating the number of bacteria associated with the relevant health parameter in your microbiome. With the algorithm developed by ENBIOSIS, an analysis approach was produced to reveal the health parameters from the microbiome profile by evaluating the microbiome data and health findings of approximately 30,000 people by using machine learning approaches.

To understand how the ENBIOSIS Microbiome Analysis Report makes this assessment, we must first address the following parameters that are associated with general health and are closely linked to the bacteria in our gut:

Carbohydrate, Protein, and Fat Metabolisms: It is known that how carbohydrates, proteins, and fats, which are the basic components of the foods we consume, are processed and converted into energy in our body is determined by the communication between our microbiome and our body. Therefore, it is possible to predict how our energy metabolism works by looking at our microbiome profile. The results of this analysis are presented through scores that evaluate these metabolisms and through a comparison of your score to those of various health groups.

Antibiotic Damage: Antibiotics, which exist as forms of drugs or additives in the foods we consume, cause significant damage to the bacterial communities in the gut, and the resulting imbalances can adversely affect health. The damage score presents the extent to which your microbiome resembles characteristics of a microbiome that has been altered as a result of antibiotic damage.

Gut Motility: Although it is known that a healthy functioning gut plays a role in the quality of health in many systems, particularly the digestive system, studies have shown that the state of the microbiome plays a role in this mobility. The score obtained from the analysis gives information about the role that the microbiome plays on gut motility.

Body Mass Index: Measurable differences have been found in the microbiomes of people in the slim, normal weight, overweight, or obese categories, as the microbiome significantly controls how the food taken in our bodies is converted into energy. From this point of view, it is possible to estimate how suitable the microbiome of a person is for weight gain/loss. With the body mass index score, it is revealed how suitable the microbiome is for weight loss/gain.

Gluten Sensitivity (Intolerance): Scientific studies conducted with individuals who have problems with gluten digestion reveal that one of the important risk factors in the triggering, emergence, or progression of sensitivity is the composition of the microbiome. This makes it possible to quantify the risk of gluten sensitivity borne by microbiome composition. The sensitivity score presented in the microbiome analysis report provides information about your risk of gluten sensitivity caused by your microbiome.

Lactose Intolerance: It is known that individuals who have problems with lactose digestion differ in their microbiome profiles. Moreover, this problem can be regressed by feeding the microbiome properly. The sensitivity score presented in the analysis reveals how much your microbiome resembles that of individuals with lactose intolerance.

Autoimmunity Index: Previous scientific experiments revealed that the gut microbiome profiles of patients suffering from many autoimmune diseases are different from that of healthy individuals. It is now strongly accepted that the imbalance of the microbiome plays a role in the development of autoimmune diseases. It has become possible to assess the risk that the microbiome poses on this disorder by grading the transition between healthy and autoimmune people using artificial intelligence methods. The index developed gives you an idea of your potential risk by presenting the extent to which your microbiome matches the microbiome characteristics of individuals with autoimmune diseases.

Probiotic Microorganisms: The presence and number of bacteria species living in our gut that are known to have positive contributions to our health is a parameter that shows how well we can benefit from these positive contributions. The relative sufficiency of the number of probiotic bacteria compared to other individuals is presented to you with this score.

Sugar Consumption: When different individuals are examined, it can be observed that the consumption of high amounts of refined sugar, which increases with a Western-style diet, causes changes in our microbiome balance. This score indicates how similar your microbiome profile is to the characteristics of individuals with high sugar consumption, and thus, presents the degree to which sugar consumption causes a change in the microbiome.

Artificial Sweetener Damage: Since they cannot be digested by humans, artificial sweeteners, which exist in our meals as calorie-free molecules, may cause toxic effects for some of our gut bacteria at the end of their journey in the digestive tract, causing their numbers to reduce and disturbances in gut balance to take place. It has further been revealed that this imbalance may play a role in the formation of chronic diseases such as metabolic syndrome. The microbiome analysis report presents how similar your profile is to the characteristics of individuals who are frequently exposed to artificial sweeteners, and thus, presents the degree to which sweeteners causes a change in the microbiome.

Sleep Quality: The microbiome profile has a direct relationship with sleep physiology due to the role of the microbiome in communication with the brain and regulation of the circadian rhythm. The suitability of your microbiome for quality sleep is measured through the relative scores presented in this report.

Vitamin Synthesis: We have known for a long time that many vitamins that are known to be necessary for our health are synthesized by gut bacteria and absorbed by the gut. This score indicates the condition of your bacteria responsible for vitamin biosynthesis compared to that of the population.

Microbiome Age: Our microbiome, which begins to form in the womb, differentiates in line with our age, and ages with us. Our living conditions and eating habits play a very important role in making our microbiome appear younger or older than our age. The change in the microbiome community as we age is so characteristic that it is possible to determine the biological age of an individual by examining the microbiome. The ENBIOSIS microbiome age estimation algorithm measures which age group your microbiome characteristics reflect the most compared to the population normal. In this way, it is possible to infer whether your microbiome ages earlier than your chronic age or remains relatively young. Recent studies report that young microbiomes have anti-aging effects because they enable the metabolism of individuals to be healthy.

Scientific research conducted over the past 15 years has revealed that our partner in life, the microbiome, is an ecosystem that has significant effects on our health. The greatest opportunity we have is the potential for a healthier life and better quality of life by managing our microbiome, especially through dietary management. However, in order to design the guidance prescriptions for the microbiome that differ from person to person, the current condition of our existing microbiome must first be understood. This is exactly what the ENBIOSIS Microbiome Analysis Report aims to present to you through its detailed and clear explanations!

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